Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based Therapies

By P. Zuk, Min Zhu, H. Mizuno, Jerry I. Huang, J. Futrell, A. Katz, P. Benhaim, H. Lorenz, M. Hedrick. Tissue engineering, 2001

7,901 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/95c9dee03a071c5716c6455284255674012ad3b1

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Citations in the corpus

Same or Not the Same? Comparison of Adipose Tissue-Derived Versus Bone Marrow-Derived Mesenchymal Stem and Stromal Cells (2012, positive): “However, it was eventually found that MSCs can be easily and safely isolated not only from bone marrow but also from other sources, including adipose tissue [10], placenta [12], umbilical cord blood [13], umbilical cord [14], and dental pulp [113].”
Biologic properties of mesenchymal stem cells derived from bone marrow and adipose tissue (2006, background): “Adipose tissue stem cells (ASCs), like bone marrow MSCs (BMSCs), differentiate in vitro toward the osteogenic, adipogenic, neurogenic, myogenic, and chondrogenic lineage when treated with established lineage specific factors [Zuk et al., 2001, 2002; Mizuno et al., 2002].”
Marrow-isolated adult multilineage inducible (MIAMI) cells, a unique population of postnatal young and old human cells with extensive expansion and differentiation potential (2004, background): “…isolated from umbilical cord blood (Erices et al., 2000), peripheral blood (Huss, 2000; Zvaifler et al., 2000; Kuci et al., 2003), adipose tissue (Zuk et al., 2001), skeletal muscle and dermis (Young 2971 We report here the isolation of a population of nontransformed pluripotent human cells from…”
Cell-Assisted Lipotransfer: Supportive Use of Human Adipose-Derived Cells for Soft Tissue Augmentation with Lipoinjection (2006, positive): “A DIPOSE-DERIVED STROMAL (STEM) CELLS (ASCs) can be obtained from liposuction aspirates 1,2 and differentiate into multiple lineages of mesodermal or ectodermal origins.”
Autologous stem cells (adipose) and fibrin glue used to treat widespread traumatic calvarial defects: case report. (2004, methodology): “dissected into small pieces, transferred into a sterile blood bag and processed according to a standardized protocol developed by MacroPore Biosurgery and the Giessen University according to Zuk et al. (2001). The process took two hours including washing steps performed with phosphate-buffered salin”
Bone regeneration strategies: engineered scaffolds, bioactive molecules and stem cells Current stage and future perspectives (2018, positive): “immunoprivileged since it was found to be protective against acute graft-versus-host disease [150].”
Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC (2011, methodology): “Different groups reported differentiation protocols for AT-MSC (ASC) by using dexamethasone, b-glycerophosphate and ascorbic acid as medium supplements [50,74,75].”
Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics (IFATS) and Science and the International Society for Cellular Therapy (ISCT) (2013, background): “A selection of lineage-specific gene or protein biomarkers can be made from the following based on published data: for adipogenesis (adiponectin, fatty acid binding protein 4, leptin, peroxisome proliferator activated receptor g, glycerol 3 phosphate dehydrogenase); for chondrogenesis, aggrecan, col”
Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. (2004, methodology): “Although the derivation of mesenchymal stem cells from adipose tissues has been reported before ( 33 ), our method gave a larger number of cells in a shorter time (32 cpdl in 51 days compared to 22 cpdl in 165 days) (28).”
Multipotent progenitor cells can be isolated from postnatal murine bone marrow, muscle, and brain. (2002, background): “The possibility exists that MSC, which can be found in tissues other than BM, such as subcutaneous fat [41], may be found in brain and muscle.”