Filaggrin in the frontline: role in skin barrier function and disease

By A. Sandilands, C. Sutherland, A. Irvine, W. McLean. Journal of Cell Science, 2009

873 citations recorded by the source corpus.

Subfields: Dermatology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/95a3ac9180bf067476488677c3da8dc710ebc0cb

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1. M. Salimi
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8. Xinwen Wang

Citations in the corpus

• Th2 Cytokines and Atopic Dermatitis (2011, background): “Most of the genetic studies relate to FLG, a keratinocyte gene that encodes profilaggrin, a large molecule composed of a dozen filaggrin repeats and a major component of keratohyaline granules, that characterize the granular layer of the epidermis [12].”
• A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis (2013, background): “Filaggrin is expressed in keratinocytes and is thought to have a role in skin barrier function, cutaneous pH, and hydration (Presland et al., 2001; Sandilands et al., 2009).”