Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells.

By A. Lanzavecchia, F. Sallusto. Science, 2000

892 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/94e06e7408d9a77b52e4b076382767b80004e9de

How researchers see this paper

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In Immunology

1. Rafi Ahmed
2. F. Sallusto
3. E. Wherry
4. A. Lanzavecchia
5. N. Restifo
6. S. Kaech
7. S. Rosenberg
8. R. Seder

Citations in the corpus

• Regulation of T cell immunity by dendritic cells. (2001, background): “…at later time points, when the influx of DCs ceases and the DCs surviving in the T cell area exhausttrigger DCs via CD40L or TRANCE, improving their T cell stimulatory capacity, boosting IL-12 production and their IL-12 producing capacity (Lanzavecchia and Sallusto, 2000).prolonging their lifespan.”
• Heterologous immunity provides a potent barrier to transplantation tolerance. (2003, background): “, CD28/B7, CD40/ CD40L) do not seem to be essential (15, 16).”
• Regulatory T cells in the control of immune pathology (2001, background): “The differentiation of naive CD4 + T cells is crucially determined by two interrelated factors: the APC that stimulates them and the cytokine environment in which the activation occur”
• Adoptive immunotherapy for cancer: building on success (2006, background): “Memory CD8 + T cells might reflect T cells arrested at intermediate stages of the differentiation pathwa”
• Similarities and differences in CD4+ and CD8+ effector and memory T cell generation (2003, background): “Such cells are at the earliest stage of differentiation and are most prevalent when naive CD4 + T cells are activated in nonpolarizing condition”
• Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming (2004, background): “Although in our system NK cells seem to be essential role in T H 1 polarization, it is possible that under other conditions they may become redundant—for example, in T H 1-prone strains of mice or when the strength of TCR stimulation or the concentration of IL-12 is very hig”
• Mixed immunotherapy and chemotherapy of tumors: modeling, applications and biological interpretations. (2006, neutral): “1× 10−7 [93], [59]”