Similarities and differences in CD4+ and CD8+ effector and memory T cell generation
By R. Seder, Rafi Ahmed. Nature Immunology, 2003
1,015 citations recorded by the source corpus.
Subfields: Immunology
View Paper: https://www.semanticscholar.org/paper/b50744bcae63ea7d16d5c2f5fdec8e4e35046117
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In Immunology
Citations in the corpus
- Immunity to malaria: more questions than answers (2008, background): “Memory CD4 + and CD8 + T cells require major histocompatibility complex class II and class I and IL-7 for maintenanc”
- A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 (2005, background): “IFN-γ and TNF are also expressed by effector CD8 T cell”
- Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control (2008, neutral): “It has been an accepted paradigm for some time that memory cells maintain full cytotoxic capacity (reviewed in Seder and Ahmed, 2003; Trambas and Griffiths, 2003).”
- Heterogeneity and cell-fate decisions in effector and memory CD8+ T cell differentiation during viral infection. (2007, background): “Effector CD4+ T cells take on a diverse set of roles and inhibit viral replication through the production of antiviral cytokines (and perhaps cytotoxicity), but they also activate dendritic cells (DCs) and provide help to B cells and CD8+ T cells (Seder and Ahmed, 2003).”
- Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes (2012, neutral): “Activated CD8+ T cells destroy β-cells either through a perforin-dependent pathway or alternatively by the Fas/FasL pathway [373, 392].”
- Stereotactic Radiation Therapy Augments Antigen-Specific PD-1-Mediated Anti-Tumor Immune Responses via Cross-Presentation of Tumor Antigen (2014, background): “For these studies, we defined na€ ve cells as CD62Lþ and CD44 (Fig.”