Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2.
By G. Spaggiari, A. Capobianco, H. Abdelrazik, F. Becchetti, M. Mingari, L. Moretta. Blood, 2008
1,042 citations recorded by the source corpus.
Subfields: Genetics, Hematology, Immunology
View Paper: https://www.semanticscholar.org/paper/94435bb17333390dc58fbe7111a68a1973019ff1
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In Immunology
Citations in the corpus
- Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC (2011, background): “A mechanism specifically suppressing NK cell functions has been shown by Spaggiari et al [ 115 ] revealing that downregulation of activating NK cell receptors NKp30 (CD337), NKp44 (CD336), and NKG2D (CD314) inhibits NK cell functions.”
- Mesenchymal stem cells in health and disease (2008, background): “However, when resting NK cells are incubated with these cytokines in the presence of MSCs, NK-cell proliferation and IFNγ production are almost completely abrogate”
- Mesenchymal Stem Cells: Mechanisms of Immunomodulation and Homing (2010, background): “Fo xp 3 I1 -1 0, T G Fb A ut oi m m un ity [ 1 53 , 1 54 ]”