The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling.

By Carol A. Grimes, R. Jope. Progress in neurobiology, 2001

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Cancer chemoprevention with dietary phytochemicals (2003, background): “GSK-3β can be inactivated by phosphorylation of serine-9, either through WNT signalling or through activation of the PI3K–AKT pathwa”
GSK-3: tricks of the trade for a multi-tasking kinase (2003, background): “We now know that, beyond its role in glycogen metabolism, GSK3 acts as a downstream regulatory switch that determines the output of numerous signalling pathways initiated by diverse stimuli (reviewed in Frame and Cohen, 2001; Grimes and Jope, 2001; Woodgett, 2001).”
Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases (2014, background): “…are Fos/Jun AP-1, CREB, heat shock factor 1, nuclear factor of activated T cells (NFAT), myc, C/EBP, NF-κB, p53, signal transducer and activator of transcription-3 (STAT3), as well as many others that have been reviewed previously (Grimes and Jope, 2001; Jope and Johnson, 2004; Sutherland, 2011).”
LTP inhibits LTD in the hippocampus via regulation of GSK3beta. (2007, positive): “Ubiquitously expressed in eukaryotes (see Ali et al., 2001), GSK3 plays a fundamental role in a wide variety of functions, including the division, proliferation, differentiation and adhesion of cells (Frame and Cohen, 2001; Grimes and Jope, 2001).”