Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway.

By C. Bai, W. Auerbach, Joon‐Sung Lee, Daniel N. Stephen, A. Joyner. Development, 2002

735 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/92a454d694db2720d1d7e6f14bf27e3bbe0a3ca8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. S. Angers
2. C. Hui
3. F. Balordi

Citations in the corpus

• Hedgehog Signaling in the Subventricular Zone Is Required for Both the Maintenance of Stem Cells and the Migration of Newborn Neurons (2007, methodology): “Moreover, as noted above, in addition to functioning to induce Gli activators, Hh signaling also can mediate the removal of Gli repressors (Wang et al., 2000; Bai et al., 2002, 2004; Fuccillo et al., 2006).”
• Gli proteins in development and disease. (2011, background): “By contrast, Gli1 is dispensable for development (Bai et al. 2002, Park et al. 2000) and appears to function as part of a positive feedback loop.”
• Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. (2003, unknown): “(Bai et al., 2002).”