Perineuronal Nets Protect Fear Memories from Erasure

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Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear (2010, positive): “True erasure of the fear memory only occurs in special circumstances, as when the fear memory is first reactivated and then the CS is repeatedly presented during the reconsolidation window, or when reconsolidation is disrupted by administration of a -adrenergic receptor antagonist prior to memory re”
Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress (2012, background): “Instead of potentiating inhibitory systems, early life extinction appears to erase fear memories from the amygdala (Kim & Richardson 2008, Gogolla et al 2009).”
The Biology of Regeneration Failure and Success After Spinal Cord Injury. (2018, background): “However, PNNs have additionally been implicated in a multitude of other homeostatic functions such as neuroprotection (43) and memory consolidation (141, 250, 308, 327).”