Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

By Lucas Pelkmans, J. Kartenbeck, Ari Helenius. Nature Cell Biology, 2001

1,333 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/9232d151a394706e4bc88028d5895d09fbc104a8

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Citations in the corpus

Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling (2005, background): “, which indicates that AMFR — similar to TGFβR, IL2Rβ, SV40 (Ref”
Distinct endocytic pathways regulate TGF-β receptor signalling and turnover (2003, background): “as well as internalization of toxins, SV40 virus and glycosyl phosphatidylinositol (GPI)-anchored protein”
Viruses and their uses in nanotechnology (2006, neutral): “In contrast to human polyoma JC virus, the uptake of mouse polyomavirus into cells is by a clathrin-independent pathway [Pelkmans et al., 2001, 2004].”
Uptake Pathways and Subsequent Intracellular Trafficking in Nonviral Gene Delivery (2006, background): “Classically, caveolae were defined as flask-shaped invaginations of the plasma membrane, but they can also be flat, tubular, or detached vesicles (Smart et al., 1999; Pelkmans et al., 2001; Harris et al., 2002).”
Feature point tracking and trajectory analysis for video imaging in cell biology. (2005, methodology): “Using frames from videos, they visualized and analyzed many of the key steps in the early pathway of the caveolar entry of SV40 into live cells (Pelkmans et al., 2001).”
Autophagy and lysosomal dysfunction as emerging mechanisms of nanomaterial toxicity (2012, background): “lysosomes, pathogens have been shown to take advantage of this pathway to escape lysosomal enzymatic degradation [17,18].”
Exosome Uptake Depends on ERK1/2-Heat Shock Protein 27 Signaling and Lipid Raft-mediated Endocytosis Negatively Regulated by Caveolin-1 (2013, background): “It has previously been shown that endocytic uptake of virus particles is negatively regulated by CAV1 by stabilization of specific plasma membrane lipid raft domains (1, 26, 27).”
The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls. (2010, background): “Certain pathogens, like SV40 virus and Cholera toxin subunit B (CTB) specifically use this pathway to enter cells and the latter is often used as a marker for this pathway [10,11].”
Matters Arising Quantitative and Dynamic Assessment of the Contribution of the ER to Phagosome Formation (2005, positive): “Material internalized by caveolar endocytosis can be delivered more directly to the ER, possibly bypassing the Golgi complex (Pelkmans et al., 2001), and a similar route may apply to vesicles derived from phagosomes, which appear to contain caveolar components (Dermine et al., 2001).”
Role of caveolae and caveolins in health and disease. (2004, background): “Additionally, the overexpression of a dominant negative caveolin mutant, which inhibits caveolar-mediated endocytosis, resulted in little or no SV40 infection (191, 204).”