Uptake Pathways and Subsequent Intracellular Trafficking in Nonviral Gene Delivery
By I. Khalil, K. Kogure, H. Akita, H. Harashima. Pharmacological Reviews, 2006
1,262 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/707845a635846813455b5c55a13fc082eee8aa4c
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Citations in the corpus
- The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls. (2010, background): “A number of endocytic pathways have been demonstrated to be involved in the uptake of DNA complexes [18-21], and this is highly dependent on cell type [22,23], the nature of the gene carrier [24,25] and the particle size [5].”
- Liposome Technology for Industrial Purposes (2010, background): “These toxic effects may result from either cationic lipids or nucleic acids [17, 18].”
- Lipid-based Nanoparticles for Nucleic Acid Delivery (2007, background): “The topics of endocytosis, subsequent endosome escape, and intracellular trafficking into the nucleus have been extensively reviewed by others (8,27,28) and will not be discussed here.”
- A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect: a strategy for overcoming the PEG dilemma. (2011, background): “endosome/lysosome degradation, [13] unlike chemotherapeutic drugs such as doxorubicin, which spontaneously accumulate in the nucleus”
- The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles (2012, neutral): “Bulk flow of substances from the extracellular space, by contrast, occurs through fluid-phase endocytosis, formerly termed pinocytosis.(155) This transport is nonsaturable and has a low capacity.”
- Exosome Uptake through Clathrin-mediated Endocytosis and Macropinocytosis and Mediating miR-21 Delivery* (2014, methodology): “K depletion presents a useful procedure to block clathrin-coated pits (28).”