Nucleosome organization in the Drosophila genome

By Travis N. Mavrich, Cizhong Jiang, I. Ioshikhes, Xiaoyong Li, Bryan J. Venters, Sara J Zanton, L. Tomsho, Ji Qi, R. Glaser, Stephan C. Schuster and 3 more. Nature, 2008

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How a protein searches for its site on DNA: the mechanism of facilitated diffusion (2009, background): “Interestingly, recently obtained maps of nucleosomes in a variety of organisms are very consistent with this picture (figure 11(D)): about 90– 99% of DNA is packed [52]and largely inaccessible [54], while regions of ≈300–500 bps in the vicinity of target sites remain available for binding and nucleo”
Distinct Modes of Regulation by Chromatin Encoded through Nucleosome Positioning Signals (2008, background): “Moreover, examining the distribution of boundaries around transcription start sites where previous studies [5,9,13] found a stereotyped nucleosome depleted region, and around translation end sites where similar depletions were observed [11,12, 26 ], we find that both the depletion level and length o”
Histone variants — ancient wrap artists of the epigenome (2010, neutral): “Z (H2Av) nucleosome, which might contribute to RNAPII pausing 70 and to TSS selection 71 .”