The growing landscape of lysine acetylation links metabolism and cell signalling

By Chunaram Choudhary, B. Weinert, Y. Nishida, E. Verdin, Matthias Mann. Nature reviews. Molecular cell biology, 2014

1,251 citations recorded by the source corpus.

Subfields: Geriatrics and Gerontology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/8ef9613fc5d8112bb2ad89ea9bd73c9b16358c4d

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Citations in the corpus

The Metabolic Signature of Macrophage Responses (2019, background): “of proteins, which is known to regulate protein function at multiple levels (81).”
Initiation and perpetuation of NLRP3 inflammasome activation and assembly (2015, background): “Therefore, altered glycolysis and oxidative phosphorylation could influence reactive oxygen species (ROS) production, new fatty acid synthesis, and membrane dynamics might be involved, and changes in citrate and succinate utilization could influence post-translational modifications (acetylation and ”
Metabolic reprogramming and epigenetic modifications on the path to cancer (2021, background): “…acetate is mediated by acyl-CoA synthetase shortchain family members (ACSSs), including ACSS1 and ACSS3 in mitochondria and ACSS2 in the cytoplasm and nucleus (Luong et al., 2000; Fujino et al., 2001; PerezChacon et al., 2009; Ariyannur et al., 2010; Choudhary et al., 2014; Comerford et al., 2014).”
The world of protein acetylation. (2016, background): “Akt phosphorylates acetylated FOXO1 concomitantly resulting in binding of the protein 14-3-3, and thus inhibiting nuclear import [167].”
Multi-dimensional roles of ketone bodies in fuel metabolism, signaling, and therapeutics (2017, background): “One role of acetyl-CoA is to serve as a substrate for acetylation, an enzymatically catalyzed histone covalent modification (Choudhary et al., 2014; Dutta et al., 2016; Fan et al., 2015; Menzies et al., 2016).”
Multidimensional proteomics for cell biology (2015, background): “By contrast, acetylation of Lys residues in a protein can block ubiquitin-dependent degradation 54 .”
Acetyl coenzyme A: a central metabolite and second messenger. (2015, background): “From archaebacteria to mammalians, acetyl-CoA occupies a critical position in multiple cellular processes, as a metabolic intermediate, as a precursor of anabolic reactions, as an allosteric regulator of enzymatic activities, and as a key determinant of protein acetylation (Choudhary et al., 2014).”