The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice.

By J. Cryan, C. Mombereau, A. Vassout. Neuroscience and Biobehavioral Reviews, 2005

1,620 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/8e585713ebae1b927e0a76b60fcf40ffd4343ea1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. K. Tye
2. H. Schmidt
3. Karl Deisseroth
4. R. Duman
5. A. Holmes
6. Avishek Adhikari
7. K. Thompson
8. Lisa A. Gunaydin

In Molecular Biology

1. Karl Deisseroth
2. H. Schmidt
3. R. Duman
4. A. Holmes
5. K. Tye
6. H. Ko
7. J. Cryan
8. Ted G. Dinan

In Social Psychology

1. A. Holmes
2. R. Duman
3. H. Schmidt
4. K. Tye
5. Avishek Adhikari
6. J. Cryan
7. Ted G. Dinan
8. J. Mogil

Citations in the corpus

• Model organisms: The ascent of mouse: advances in modelling human depression and anxiety (2005, positive): “A related but not synonymous task is the tail suspension test (TST), in which mice hung upside-down by their tail also exhibit passive immobility after minutes of futile struggling, which emerged in the mid-1980s (Ref”
• Rodent Models of Depression: Forced Swim and Tail Suspension Behavioral Despair Tests in Rats and Mice (2007, methodology): “Nonetheless, the general level of reproducibility between laboratories using numerous strains of mice is remarkably high (Cryan et al., 2005).”
• Dopamine neurons modulate neural encoding and expression of depression-related behaviour (2012, background): “Primary categories of depression assays in rodents involve well-validated tests of motivation and anhedonia 12–15 in which performance degrades with chronic stress and improves with chronic antidepressant-medication treatment 13,15 .”
• The role of neurotrophic factors in adult hippocampal neurogenesis, antidepressant treatments and animal models of depressive-like behavior (2007, background): “Furthermore, the FST may yield false-positive results when testing antidepressant candidates that have motor activating effects (Cryan et al., 2005b).”
• Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease. (2019, methodology): “To assess depressive-like symptoms, the mice were evaluated by the tail suspension test and forced swim test (Figures 5J and 5K; Video S5; Cryan et al., 2005; Porsolt et al., 1978; Steru et al., 1985).”