Synaptic plasticity and dynamic modulation of the postsynaptic membrane

By C. Lüscher, R. Nicoll, R. Malenka, D. Muller. Nature Neuroscience, 2000

686 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8e2eb6bca40d053fad4050ed882439cd6b564802

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Malenka
2. M. Sheng
3. Michael D. Ehlers
4. A. Citri
5. R. Malinow
6. C. Lüscher
7. T. Soderling
8. Barry J. Everitt

In Molecular Biology

1. R. Malenka
2. Michael D. Ehlers
3. R. Malinow
4. M. Sheng
5. A. Citri
6. T. Soderling
7. E. Beattie
8. C. A. Barnes

Citations in the corpus

• Psychomotor Stimulant Addiction: A Neural Systems Perspective (2002, background): “On the basis of studies in the hippocampus, a model has been proposed to explain the sequential changes that may lead from LTP and LTD to alterations in the biochemical composition of the postsynaptic membrane and ultimately to changes in the structure of dendritic spines (Lüscher et al., 2000).”
• AMPA Receptor Trafficking and the Control of Synaptic Transmission (2001, background): “…is a powerful way to control the ing a cell biological basis for controlling the synapticstrength of synaptic transmission, which is important level of AMPA receptors and hence postsynaptic re-for information storage in the brain. sponsiveness (Lüscher et al., 2000; Malinow et al., 2000).”
• Training-induced structural changes in the adult human brain. (2008, background): “At the cellular level different neurotransmitters released by neuromodulatory systems were found to modify the mechanisms of long-term potentiation (LTP) and long-term depression (LTD) considered as crucial for information storage in the mammalian cell [38,74].”
• Sparseness constrains the prolongation of memory lifetime via synaptic metaplasticity. (2008, background): “Synaptic physiology, however, has shifted the view on synaptic plasticity from a continuous modification of coupling strength to a switching between stable discrete states (for review, see Lüscher et al. 2000; Lüscher and Frerking 2001; Kullmann 2003; Montgomery and Madison 2004).”
• Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system (2003, background): “jpg" NDATA ITEM> ]> The remodeling of synapses is a fundamental mechanism for information storage and processing in the brai”
• Heterosynaptic Plasticity Prevents Runaway Synaptic Dynamics (2013, background): “…further reason for the highly asymmetrical distribution of experimentally measured synaptic weights, with a large number of zero weights, could be the presence of silent synapses, at which only NMDA, but no AMPA, receptors are present (for review, see Lüscher et al., 2000; Malinow et al., 2000).”
• Frontiers in Computational Neuroscience Computational Neuroscience Structural Plasticity Controlled by Calcium Based Correlation Detection (2008, neutral): “In the section " Sensitivity of Results to Model Assumptions " we discuss an extension of our model to incorporate the LTD window for negative relative timing and we argue that our results are invariant under this modifi cation.”
• Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms (2008, background): “…24 .............................................................................................................................................. Neuropsychopharmacology REVIEWS REVIEW potentiated synapses (Luscher et al, 2000).”
• Glia-derived D-serine controls NMDA receptor activity and synaptic memory. (2006, background): “Ca2+ entry during NMDAR stimulation can trigger intracellular second messenger pathways leading to persistent changes of EPSC amplitude due to the insertion or removal of AMPARs from synapses (Luscher et al., 2000; Nicoll, 2003).”