Calcium stores regulate the polarity and input specificity of synaptic modification

By M. Nishiyama, Kyonsoo Hong, K. Mikoshiba, Mu-Ming Poo, K. Kato. Nature, 2000

691 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/8c98d051f0f048e1020096739be4d541af514188

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Distinct coincidence detectors govern the corticostriatal spike timing‐dependent plasticity (2010, methodology): “Classical models for STDP propose NMDA receptors (NMDARs) as the unique coincidence detector (Nishiyama et al. 2000; Shouval et al. 2002).”
Inositol trisphosphate and calcium signalling mechanisms. (2009, background): “The metabotropic receptors, which are also located on the spines, are responsible for generating IP3 that contributes to the process of long-term depression (LTD) that is responsible for motor learning.”
Long-term depression in the CNS (2010, background): “In addition, Ca 2+ entry triggers Ca 2+ release from intracellular store”
What's a cerebellar circuit doing in the auditory system? (2004, background): “tribution differs in fusiform and cartwheel cells (Table 1). The activation of these receptors has been shown in other cells to affect LTP and LTD differentially and to regulate the spatial distribution of plasticity [33, 34 ].”
Spike timing-dependent plasticity: from synapse to perception. (2006, background): “Although such a pre-post LTD window has been found in hippocampal slices (81), it was not reported in any other study.”
Dendritic excitability and synaptic plasticity. (2008, neutral): “(558) induced long-term plasticity with K channels blocked by internal Cs .”
Spike Timing Dependent Plasticity: A Consequence of More Fundamental Learning Rules (2010, neutral): “For example, at connections between mammalian pyramidal neurons (Markram et al., 1997; Bi and Poo, 1998; Feldman, 2000; Nishiyama et al., 2000; Sjöström et al., 2001; Wittenberg and Wang, 2006) a pre-synaptic spike preceding a postsynaptic spike within a narrow time window leads to long-term…”
Locally dynamic synaptic learning rules in pyramidal neuron dendrites (2007, positive): “Ca 2 1 release from intracellular stores has been implicated in the heterosynaptic spread of some forms of synaptic plasticity 35,36 .”
Reading the patterns in living cells —the physics of ca2+ signaling (2004, background): “It was suggested that Ca2þ waves propagated by IP3R even regulate polarity and input specificity of synaptic modification [394, 395].”
Conservation of total synaptic weight through balanced synaptic depression and potentiation (2003, background): “, and that propagating waves of such release regulate heterosynaptic changes in other cell type”