Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis

By J. Naglik, S. Challacombe, Bernhard Hube. Microbiology and Molecular Biology Reviews, 2003

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Candida Infections of the Genitourinary Tract (2010, neutral): “Other human studies also reported differential expression of Saps in patients with VVC and RVVC or asymptomatic carriers (150, 151, 176).”
Candida albicans biofilms: development, regulation, and molecular mechanisms (2016, background): “albicans that can cause injury to host tissues and, in turn, free nutrients, such as 504 amino acids and carbon sources [67].”
Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options. (2013, background): “The functionality of SAP7 has not been fully discovered, but reports exist that Sap9 and Sap10 are not secreted proteinases; instead, they are used in preserving the regulatory surface integrity of the yeast cells (Naglik et al., 2003).”
Candida albicans morphogenesis and host defence: discriminating invasion from colonization (2011, neutral): “, and the damage occurs through the production of lytic enzymes such as secreted aspartyl proteinases (SAPs”