Candida albicans biofilms: development, regulation, and molecular mechanisms

By M. Gulati, C. Nobile. Microbes and infection, 2016

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A major virulence attribute of Candida albicans is its ability to form biofilms, densely packed communities of cells adhered to a surface. These biofilms are intrinsically resistant to conventional antifungal therapeutics, the host immune system, and other environmental factors, making biofilm-associated infections a significant clinical challenge. Here, we review current knowledge on the development, regulation, and molecular mechanisms of C. albicans biofilms.

Subfields: Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/e798f3b65527bd6cc9f5091717b9fe8dbe04f0f0