Faculty Opinions recommendation of Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.
By E. Selker. 2005
309 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/89eebe00f5b80caad16bb28b134c674fe1ff0615
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In Molecular Biology
Citations in the corpus
- Small RNAs in transcriptional gene silencing and genome defence (2009, background): “RITS also physically associates with and is required for recruitment of the RNA-directed RNA polymerase complex (RDRC) to non-coding RNAs that are transcribed from centromeric repeat”
- RNA meets chromatin. (2005, background): “Moreover, both RITS and RDRC localize to noncoding centromeric transcripts (Motamedi et al. 2004).”
- RNAi-mediated chromatin silencing in fission yeast. (2008, background): “Mutations which destroy this activity cause phenotypes equivalent to those observed in cells lacking RNAi (Motamedi et al. 2004; Sugiyama et al. 2005).”
- The diverse functions of histone lysine methylation (2005, background): “Central to the targeting mechanism are two protein complexes, known as RNA-induced transcriptional silencing (RITS) and RNA-directed RNA polymerase (RDRC) 42,43 (FIG.”