P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA unction.

By Kristin D. Kasschau, Zhixin Xie, Edwards Allen, C. Llave, Elisabeth J. Chapman, Kate A. Krizan, James C. Carrington. Developmental Cell, 2003

958 citations recorded by the source corpus.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/89829cd859e8d47a5b180b25e738a72a7c64efa5

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Citations in the corpus

High-Throughput Sequencing of Arabidopsis microRNAs: Evidence for Frequent Birth and Death of MIRNA Genes (2007, methodology): “miRNA target validation assays Target validation using a 59 RACE assay was done with the GeneRacer Kit (Invitrogen, CA) as described previously [22,34,53,54].”
RNA silencing in plants (2004, background): “thaliana plants infected with turnip mosaic virus, the symptoms include developmental defects that are mimicked by transgenic expression of the HCPro suppressor of silencing, or by mutation affecting the DCL1 protein of the miRNA pathwa”
Viral RNA silencing suppressors inhibit the microRNA pathway at an intermediate step. (2004, background): “The ARF8, ARF10, or SCL6-IV mRNAs are targeted by three different miRNAs (Llave et al. 2002b; Rhoades et al. 2002; Kasschau et al. 2003).”
Computational prediction of miRNAs in Arabidopsis thaliana. (2005, background): “2C), as has also been observed for previously reported miRNAs, but not commented on (Kasschau et al. 2003).”
Microarray analysis of microRNA expression in the developing mammalian brain (2004, background): “In contrast, although some plant microRNAs with partially complementary target sites also act by preventing translation, the majority studied so far cause the cleavage of target mRNAs at sites perfectly complementary to the microRNAs [33-38].”
A pathway for the biogenesis of trans-acting siRNAs in Arabidopsis. (2005, background): “1A); this is the pattern expected for cleavage mediated by a miRNA or siRNA (Elbashir et al. 2001; Llave et al. 2002b; Kasschau et al. 2003).”
Temporal regulation of shoot development in Arabidopsis thaliana by miR156 and its target SPL3 (2006, background): “*Author for correspondence (e-mail: spoethig@sas.upenn.edu) Accepted 6 July 2006 D E V E LO P M E N T 3540 constitutively overexpress miR156b (Schwab et al., 2005), but only two of these transcripts have been shown to be cleaved by this miRNA (Chen et al., 2004; Kasschau et al., 2003).”
Endogenous siRNA and miRNA targets identified by sequencing of the Arabidopsis degradome. (2008, positive): “The Arabidopsis Degradome Generally Reflects Transcript Abundance Although plant miRNAs can interact with target transcripts without directing their hydrolysis [7, 8], the most common outcome of pairing to known targets is miRNA-directed cleavage at the tenth nucleotide of complementarity relative t”
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. (2005, background): “Cloning of the 3# cleavage products resulting from near-perfect duplex formation between a miRNA and an mRNA sequence has been a powerful means of experimentally validating targets of miRNA action (Jones-Rhoades and Bartel, 2004; Kasschau et al., 2003; Llave et al., 2002; Mansfield et al., 2004; T”
Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs. (2004, background): “The absence of full-length spliced or unspliced EST in the Arabidopsis database suggests that the This pathway differs from the heterochromatic siRNA pathway, which requires DCL3 and RDR2 but not SGS3 At2g27400 gene is not strongly transcribed or that the primary RNA and its spliced product are imme”
Control of leaf morphogenesis by microRNAs (2003, background): “The importance of miRNAs for plant development is supported by the abnormalities seen in several mutants or transgenic plants with general defects in miRNA accumulation or activit”
microRNA-directed phasing during trans-acting siRNA biogenesis in plants. (2005, methodology): “Experimental validation involved 5#RACE assays to detect a cleavage site opposite of position 10 from the 5# end of the miRNA (Kasschau et al., 2003; Llave et al., 2002).”