The dynamic range of protein expression: A challenge for proteomic research
By G. Corthals, V. Wasinger, D. Hochstrasser, Jean-Charles Sanchez. Electrophoresis, 2000
594 citations recorded by the source corpus.
Subfields: Molecular Biology, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/89234199324457c81990c374ed59d4a538ad7e51
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- John R. Yates III
- Matthias Mann
- Shao-En Ong
- M. Washburn
- Dirk Wolters
- Timothy A. J. Haystead
- Paul Graves
- R. Aebersold
In Spectroscopy
- John R. Yates III
- Matthias Mann
- Shao-En Ong
- M. Washburn
- Dirk Wolters
- R. Aebersold
- Timothy A. J. Haystead
- Paul Graves
Citations in the corpus
- Molecular Biologist's Guide to Proteomics (2002, background): “This problem cannot be overcome by simply loading more protein on the gel, because the resolution will decrease and the comigration of proteins will increase (36).”
- Large-scale analysis of the yeast proteome by multidimensional protein identification technology (2001, background): “Portions of proteomes such as proteins with extremes in pI and molecular weigh”
- Mass spectrometry–based proteomics turns quantitative (2005, background): “Furthermore, the dynamic range of protein expression can vary by as much as 7 to 12 orders of magnitude within a biological sample like seru”