Fibulin-5/DANCE is essential for elastogenesis in vivo
By Tomoyuki Nakamura, Pilar Ruiz Lozano, Y. Ikeda, Y. Iwanaga, A. Hinek, S. Minamisawa, Ching-Feng Cheng, Kazuhiro Kobuke, N. Dalton, Y. Takada and 4 more. Nature, 2002
641 citations recorded by the source corpus.
Subfields: Cancer Research, Genetics, Immunology and Allergy
View Paper: https://www.semanticscholar.org/paper/890e494445d41ef1d6b8d5eea3207eb38cd8fb32
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Citations in the corpus
- Elastic fibres. (2002, background): “It binds strongly to tropoelastin in a calcium-dependent manner, but not to fibrillin-1, and colocalises with tropoelastin (Nakamura et al., 2002; Yanagisawa et al., 2002).”
- Dysregulation of TGF-β activation contributes to pathogenesis in Marfan syndrome (2003, background): “During alveologenesis, tropoelastin is deposited by smooth muscle cells and plausibly has a spatially instructive role for septatio”
- Extracellular control of TGFβ signalling in vascular development and disease (2007, background): “It is notable in this context that mice lacking the extracellular protein fibulin-5 have fragmented elastin and tortuous elongated aortae, but do not develop aortic aneurysms or dissection”
- Elastic fiber homeostasis requires lysyl oxidase–like 1 protein (2004, background): “Gene targeting studies show that fibulin-5 is required for elastic fiber developmen”
- The Extracellular Matrix In Development and Morphogenesis: A Dynamic View (2009, background): “Loss of fibulin-4 or -5 causes reduced elasticity in the lungs, skin and vasculature leading to malformations such as loose skin and contorted aortas (McLaughlin et al., 2006; Nakamura et al., 2002; Yanagisawa et al., 2002).”