CD133, a novel marker for human prostatic epithelial stem cells

By G. Richardson, C. Robson, S. Lang, D. Neal, N. Maitland, A. Collins. Journal of Cell Science, 2004

780 citations recorded by the source corpus.

Subfields: Immunology, Oncology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/87b4f46fd8472f6f8aef27030ff11495d52f1c8c

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In Immunology

M. Wicha

In Oncology

Citations in the corpus

Prospective identification of tumorigenic prostate cancer stem cells. (2005, background): “We have previously established that the phenotype a2h1 /CD133 determines normal prostate epithelial stem cells (11).”
Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment (2009, background): “CD133 (prominin-1), a five-transmembrane glycoprotein, was initially described as a marker specific for CD34 human hematopoietic progenitor cells (19, 20), normal stem cells of the neural (21, 22), epithelial (23, 24), and endothelial lineages (25), and their tumoral counterparts (14–16, 26, 27).”
Cancer stem cells: an old idea--a paradigm shift. (2006, background): “In contrast, 105 CD133− cells engrafted but did not produce a tumor.”
SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma (2009, background): “, 2007) and prostate cancer (Richardson et al., 2004).”
Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys. (2006, background): “To identify multipotent progenitors and/or SC in adult human kidney, we assessed the presence of both CD24, a surface molecule that has been used to identify different types of human SC (16,17) and also is expressed by uninduced metanephric mesenchyme during renal embryogenesis (18), and CD133, a ma”
Molecular genetics of prostate cancer: new prospects for old challenges. (2010, background): “In independent studies, a2b1 integrin CD133 basal cells also correspond to an enriched stem cell fraction in human prostate epithelium (Richardson et al. 2004).”