Spectrum of Mutations in Long-QT Syndrome Genes: KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

By I. Splawski, Jiaxiang Shen, K. Timothy, M. Lehmann, S. Priori, Jennifer L. Robinson, A. Moss, P. Schwartz, J. Towbin, G. Vincent and 1 more. Circulation, 2000

1,303 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/85db38040e333ef7204f7d897efbf566a85418fc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. Adam P. Hill
2. Jamie I. Vandenberg
3. M. Perrin
4. R. Kass
5. J. Nerbonne
6. Stefan A. Mann
7. M. Perry
8. Ying Ke

In Molecular Biology

1. Adam P. Hill
2. Jamie I. Vandenberg
3. M. Perrin
4. R. Kass
5. J. Nerbonne
6. Stefan A. Mann
7. M. Perry
8. Ying Ke

Citations in the corpus

• Molecular physiology of cardiac repolarization. (2005, background): “Although the resolution of this seeming controversy must await further experimentation, particularly biochemical studies, it is reasonable to conclude that MiRP1 (KCNE2) is functionally important in the regulation of myocardial membrane excitability, as evidenced by the fact that KCNE2 variants are ”
• hERG K(+) channels: structure, function, and clinical significance. (2012, background): “Mutations in KCNEs are associated with both inherited long QT syndrome (LQTS) (3, 72, 441, 589) as well as drug-induced QT prolongation (1, 565), which is consistent with KCNEs modulating IKr in native tissue.”