The negative regulator of plant cold responses, HOS1, is a RING E3 ligase that mediates the ubiquitination and degradation of ICE1.

By C. Dong, Manu Agarwal, Yiyue Zhang, Q. Xie, Jian‐Kang Zhu. Proceedings of the National Academy of Sciences of the United States of America, 2006

694 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/84dc76d126e100a5057be9281e6a6a7fec23739e

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Citations in the corpus

Ethylene Signaling Negatively Regulates Freezing Tolerance by Repressing Expression of CBF and Type-A ARR Genes in Arabidopsis[W][OA] (2012, background): “Cold stress activates CBF expression (Gilmour et al., 1998; Liu et al., 1998) and induces the expression of a large subset of COR genes (Maruyama et al., 2004; Vogel et al., 2005), and the overexpression of CBFs leads to constitutively enhanced freezing tolerance (Jaglo-Ottosen et al., 1998; Liu et ”
Cold stress regulation of gene expression in plants. (2007, background): “These results demonstrate that HOS1ubiquitinates ICE1 to regulatenegatively the expression of ICE1 target genes (Figure 1), and is thus critical for the de-sensitization of plant cells to cold stress [ 68 ].”
Firefly Luciferase Complementation Imaging Assay for Protein-Protein Interactions in Plants1[C][W][OA] (2007, methodology): “BiFC is relatively simple compared to FRET and BRET and has been used in a number of plant protein-protein interaction studies (Bracha-Drori et al., 2004; Walter et al., 2004; Dong et al., 2006; Quan et al., 2007).”
Molecular Basis of Plant Cold Acclimation: Insights Gained from Studying the CBF Cold Response Pathway1 (2010, background): “This activation process, however, is countered by HOS1, a RING finger E3 ligase that mediates ubiquitination and degradation of ICE1 (Lee et al., 2001; Dong et al., 2006).”
SIZ1-Mediated Sumoylation of ICE1 Controls CBF3/DREB1A Expression and Freezing Tolerance in Arabidopsis[W][OA] (2007, methodology): “In Vitro Ubiquitination of ICE1 Arabidopsis MBP-HOS1 (cDNA clone was kindly provided by Jian-Kang Zhu; Dong et al., 2006) was purified using amylose resin (New England Biolabs) as instructed.”
Over-expression of miR397 improves plant tolerance to cold stress in Arabidopsis thaliana (2014, background): “ICE1 is regulated by ubiquitylation (Dong et al. 2006) and sumoylation (Miura et al.”
Jasmonate Regulates the INDUCER OF CBF EXPRESSION–C-REPEAT BINDING FACTOR/DRE BINDING FACTOR1 Cascade and Freezing Tolerance in Arabidopsis[W] (2013, background): “Moreover, the SMALL UBIQUITINRELATED MODIFIER E3 ligase SIZ1 (SAP and Miz) and the ubiquitin E3 ligase HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 have been shown to modify ICE1 posttranslationally and function in the ICE-CBF/DREB1 signaling pathway (Dong et al., 2006; Miura et al., 2007).”
Abiotic stress response in plants : when post-transcriptional and post-translational regulations control transcription (2008, background): “Alternatively HOS1 can cause ubiquitination of ICE1 and consequently its proteosomal degradation [93].”
Small RNAs as big players in plant abiotic stress responses and nutrient deprivation. (2007, background): “The HOS1 (high expression of osmotically responsive genes 1) protein, a ubiquitin E3 ligase, negatively regulates cold responses through the ubiquitination of ICE1 [ 55 ].”
Genomics of Cold Hardiness in Woody Plants (2014, background): “The stabilization by AtSIZ1 is counteracted by the ubiquitination and subsequent degradation of AtICE1 due to the RING finger E3 ligase AtHOS1 (Dong et al., 2006), which transfers into the nucleus, where AtICE1 is, in response to low temperatures (Miura et al.”
Plant abiotic stress response and nutrient use efficiency (2020, background): “For example, ICE1 can be ubiquitinated by high expression of osmotically responsive gene 1 (HOS1), a RING-finger ubiquitin E3 ligase that mediates the degradation of ICE1 through the 26S proteasome pathway under cold stress (Dong et al., 2006).”
Cold stress and acclimation - what is important for metabolic adjustment? (2010, background): “The HOS1 product is a RING E3 ligase targeting ICE1 for degradation in the proteasome (Dong et al. 2006).”