Toll-Like Receptor 8-Mediated Reversal of CD4+ Regulatory T Cell Function

By Guangyong Peng, Zhong Guo, Y. Kiniwa, K. Voo, Weiyi Peng, T. Fu, Daniel Y Wang, Yanchun Li, Helen Y Wang, Rong‐Fu Wang. Science, 2005

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Subfields: Immunology

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The perfect mix: recent progress in adjuvant research (2007, background): “31 ), or to reverse their inhibitory effect, as has been shown for TLR8 (Ref”
Innate immunity of the newborn: basic mechanisms and clinical correlates (2007, background): “or by direct effects (through activation of TLR8 on T Reg cells”
Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1 (2012, neutral): “; Hirashima, Mitsuomi; Uede, Toshimitsu; Takaoka, Akinori; Yagita, Hideo; Jinushi, Masahisa Citation Nature Immunology, 13(9): 832-842”
Translating innate immunity into immunological memory: implications for vaccine development. (2006, result): “Furthermore, similar to in recent studies with memory B cells (McHeyzer-Williams and McHeyzer-Williams, 2005), certain subsets of T cells express TLRs (Peng et al., 2005).”