Molecular mechanisms of copper uptake and distribution.

By S. Puig, D. Thiele. Current Opinion in Chemical Biology, 2002

694 citations recorded by the source corpus.

Subfields: Hematology, Nutrition and Dietetics, Oncology

View Paper: https://www.semanticscholar.org/paper/84369dd5082667c243ee5919121f85d9c63399ad

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In Hematology

1. I. Yruela
2. A. Manara

In Nutrition and Dietetics

1. I. Yruela
2. A. Manara
3. G. Grass
4. C. Rensing

In Oncology

1. I. Yruela
2. A. Manara

Citations in the corpus

• Plant Responses to Heavy Metal Toxicity (2012, background): “CTR proteins comprise a putative metal-binding motif in the extracellular domain, three predicted transmembrane domains, and a conserved and essential MXXXM motif within the putative second transmembrane domain (Puig and Thiele 2002).”
• Heavy metal stress and responses in plants (2019, background): “Recent studies have revealed that Cu transporters, exhibiting high affinity, can be located on plasma membrane in various different organisms (Puig and Thiele 2002).”
• Copper in plants: acquisition, transport and interactions. (2009, methodology): “1 COPT copper transporters COPper Transporter Protein (COPT) family has been identified in plants by sequence homology with the eukaryotic Cu transporters named Ctr or by functional complementation in yeast (for reviews Peña et al. 1999; Labbé and Thiele, 1999; Harris 2000; Puig and Thiele 2002; Pui”
• Copper in plants (2005, background): “All members belonging to the Ctr family contain three predicted transmembrane segments and most posses a N-terminal Met- and His- rich putative metal binding domain (for reviews Peña et al., 1999; Labbé and Thiele, 1999; Harris, 2000; Puig and Thiele, 2002).”
• Survival strategies of arbuscular mycorrhizal fungi in Cu-polluted environments (2009, neutral): “…on how Cu gets into the fungus, although the most likely mechanism is via a member of an evolutionary conserved family of transporters called the Copper Transporter family (Ctr1), which mediates high-affinity Cu transport into cells of all eukaryotic organisms studied (Puig and Thiele 2002).”
• Indigenous microorganisms as potential bioremediators for environments contaminated with heavy metals (2012, neutral): “All living organisms require copper as a catalytic cofactor for basic biological process such as respiration (Puig and Thiele, 2002).”
• Escherichia coli mechanisms of copper homeostasis in a changing environment. (2003, background): “High-a⁄nity copper uptake is energy dependent and speci¢c for Cu(I) over other metals [2].”
• Copper homeostasis and cuproptosis in health and disease (2022, background): “Cu uptake into cells The high-affinity Cu transporter CTR1 (also known as SLC31A1) is structurally and functionally conserved from yeast to humans and is responsible for the majority of Cu uptake into cells.(25) A growing body of evidence suggests that CTR1 transports Cu, and Ctr1 may function toget”
• Functions and Homeostasis of Zinc, Copper, and Nickel in plants (2005, neutral): “2), which is ubiquitous in eukaryotes (Puig and Thiele 2002).”
• Mechanisms for copper acquisition, distribution and regulation. (2008, background): “Moving copper into cells One mode for specific, high-affinity Cu import into eukaryotic cells is via Ctr1, an integral membrane protein that is structurally and functionally conserved from yeast to human”