Pore-forming toxins: ancient, but never really out of fashion

By M. D. Peraro, G. V. D. Goot. Nature Reviews Microbiology, 2015

701 citations recorded by the source corpus.

Subfields: Ecology, Infectious Diseases, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/841056e5a8998388273147028cbb79c78e844a5e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Corey Rogers
2. E. Alnemri
3. T. Fernandes-Alnemri
4. Lindsey Mayes
5. Diana Alnemri
6. G. Cingolani
7. Kate Schroder
8. M. Fricker

Citations in the corpus

• Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death (2017, positive): “In analogy to other pore-forming toxins 33 , we propose DFNA-5N-terminal moiety undergoes a complex conformational change upon oligomerization that results in formation of a membrane penetrating-tip (Supplementary Fig.”