Mitochondrial mutations in cancer
By Marty C. Brandon, Pierre Baldi, Douglas C. Wallace. Oncogene, 2006
835 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/82804bf5b20b79270dad809811a1bfec5385d0d8
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cancer Research
- Guido Kroemer
- Douglas C. Wallace
- Vincent Procaccio
- J. Pouysségur
- G. Barrera
- D. Hanahan
- R. Weinberg
- Anthony Kar Lun Leung
In Molecular Biology
- Douglas C. Wallace
- Guido Kroemer
- Vincent Procaccio
- Marty C. Brandon
- Pierre Baldi
- J. Pouysségur
- Niranjan Nagarajan
- Andreas Wilm
Citations in the corpus
- Tumor cell metabolism: cancer's Achilles' heel. (2008, background): “Mitochondrial DNA (mtDNA) mutations may arise as a result of tumor progression (Brandon et al., 2006), but some mtDNA mutations might actively contribute to tumor progression.”
- An enhanced MITOMAP with a global mtDNA mutational phylogeny (2006, background): “Since mtDNA mutations can arise in both the germline and somatic tissues, they have been associated with both degenerative diseases and cancers (4–6).”
- Oxidative Stress and Lipid Peroxidation Products in Cancer Progression and Therapy (2012, background): “The decomposition of hydrogen peroxide to water and oxygen is further catalyzed by catalase.”
- Oxidative Stress, Mitochondrial Dysfunction, and Aging (2011, background): “A better understanding of response to oxidative stress and mitochondrial dynamics will lead to new therapeutic approaches for the prevention or amelioration of age-associated degenerative diseases.”
- LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets (2012, background): “Heteroplasmic mitochondrial DNA (mtDNA) mutations (present in only a fraction of the mtDNA) are often disease related and have been associated with tumor activity and cancer etiology (42,43).”
- Excitotoxicity: bridge to various triggers in neurodegenerative disorders. (2013, background): “Under normal conditions, calcium induced depolarization activates mitochondrial dehydrogenases and mitochondrial ATP synthase (Brandon et al., 2006).”