Timing of antibiotic administration and outcomes for Medicare patients hospitalized with community-acquired pneumonia.

By P. Houck, D. Bratzler, W. Nsa, A. Ma, J. Bartlett. Archives of Internal Medicine, 2004

800 citations recorded by the source corpus.

Subfields: Critical Care and Intensive Care Medicine, Emergency Medicine, Epidemiology

View Paper: https://www.semanticscholar.org/paper/8126303e5dc2aa8592fbdddca44f4d76ec7be95a

How researchers see this paper

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In Critical Care and Intensive Care Medicine

1. Mitchell M. Levy
2. Theodore J. Iwashyna
3. J. Bartlett

In Epidemiology

1. Mitchell M. Levy

Citations in the corpus

• The Timing of Early Antibiotics and Hospital Mortality in Sepsis (2017, background): “While no one recommends delaying antibiotics for sepsis patients, the existing evidence supporting the mortality benefits of earlier antibiotic administration is mixed.(14-30, 32) In a frequently cited study, Kumar and others retrospectively evaluated 2,154 critically ill patients with septic shock ”
• Assessment of Clinical Criteria for Sepsis (2016, neutral): “(%) 17 327 (12) 2153 (27) 6517 (10) 2171 (27) 6486 (10)”
• BTS guidelines for the management of community acquired pneumonia in adults: update 2009 (2009, background): “Delay in prescribing antibiotics for patients in hospital with diagnosed pneumonia is associated with a worse outcome”
• Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults (2007, methodology): “Data from the Medicare database indicated that antibiotic treatment before hospital admission was also associated with lower mortality [109].”
• Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour: Results From a Guideline-Based Performance Improvement Program* (2014, background): “More recently, Houck et al (11) described that among 13,771 patients who had not received outpatient antibiotic agents, antibiotic administration within 4 hours of arrival at the hospital was associated with reduced in-hospital mortality (6.”
• Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study. (2005, methodology): “The new trial should incorporate recent guidelines for the management of patients with severe sepsis and septic shock (36), evaluate adrenal reserve in patients with septic shock (34), record timing to initial antibiotic administration ( 37 ), and obtain serial measurements of circulating inflammato”
• Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock* (2006, background): “In serious human infections, rapidity of antimicrobial therapy following presentation has been understood to be a critical determinant of outcome for specific conditions including community-acquired pneumonia (7, 9, 14, 17), ventilator-associated pneumonia (11), meningitis (10, 13), bacteremia (14, ”