The spindle checkpoint: structural insights into dynamic signalling

By A. Musacchio, K. Hardwick. Nature reviews. Molecular cell biology, 2002

603 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/811bc3d2edb1572d08f8ec97952a667b5b48e110

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. A. Musacchio
2. Hongtao Yu
3. Xuelian Luo
4. Stephen S. Taylor
5. E. Salmon
6. J. Peters
7. N. Keen

In Molecular Biology

1. A. Musacchio
2. Hongtao Yu
3. Xuelian Luo
4. Stephen S. Taylor
5. E. Salmon
6. J. Peters

Citations in the corpus

• Aurora-kinase inhibitors as anticancer agents (2004, background): “Consequently, eukaryotes have evolved a surveillance mechanism, the 'spindle checkpoint', which prevents anaphase and mitotic exit until all the chromosomes are correctly aligned (for reviews, see Ref”
• Chromosomal passengers: conducting cell division (2007, neutral): “The spindle checkpoint ( Box 1 ) is a quality-control circuit that blocks anaphase onset until all chromosomes have achieved a bipolar attachment to the mitotic spindl”
• The spindle-assembly checkpoint in space and time (2007, background): “pl?locus=bub3"> BUB3 , was identified as an extra-copy suppressor of the bub1-1 mutan”
• Recycling the Cell Cycle Cyclins Revisited (2004, neutral): “A model in which Cdc20 is a targeting device (Figure 6) can explain these checkpoint’s warhead (reviewed in Musacchio and Hardwick, 2002).”
• Riding the DUBway: regulation of protein trafficking by deubiquitylating enzymes (2006, neutral): “The seven known human Noxs include Nox1–5 and Duox1–2, with Nox2 (gp91”
• The Mad2 spindle checkpoint protein has two distinct natively folded states (2004, background): “This unusual binding mechanism may prolong the lifetimes of the Mad2-containing protein complexe”
• The anaphase promoting complex/cyclosome: a machine designed to destroy (2006, background): “Several proteins have been identified that are required for a functional spindle-assembly checkpoint and that are enriched on unattached kinetochores where checkpoint signalling is initiated (reviewed in Ref”