Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3

By R. Dammann, Chun Xing Li, J. Yoon, Philip L. Chin, S. Bates, G. Pfeifer. Nature Genetics, 2000

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Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours (2002, background): “Finally, in the spirit of brevity, we will only mention other key targets of methylation-associated silencing in human tumours: the pro-apoptotic death-associated protein kinase (DAPK) [32,33]; the p53 homologue p73 [34]; the kidney tumour and haemangioblastomarelated von Hippel–Lindau gene (VHL) [3”
CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future (2002, background): “Many recent publications have reported genes that undergo methylation-related silencing around the same chromosomal region in 3p (exemplified in Dammann et al., 2000; Zochbauer-Muller et al., 2001b; Tomizawa et al., 2001).”
Epigenetic Determinants of Cancer. (2016, background): “Examples include RasFF1a and FHIT, located on chromosome arm 3p, frequently deleted in lung and other types of tumors (Dammann et al. 2000; Burbee et al. 2001).”