Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.
By H. Ryoo, T. Gorenc, H. Steller. Developmental Cell, 2004
619 citations recorded by the source corpus.
Subfields: Epidemiology, Immunology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/80f22ffbaf80527829a8e461df909bdbdebdd554
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In Immunology
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In Molecular Biology
Citations in the corpus
- Resolution of inflammation: the beginning programs the end (2005, neutral): “Furthermore, in Drosophila melanogaster , apoptotic cells express the secretory factor wingless and can directly stimulate cell proliferatio”
- IAPs, RINGs and ubiquitylation (2005, background): “A recent paper also shows that DRONC levels are higher in DIAP1 RING mutant cells (which have been kept alive by overexpression of the baculoviral caspase inhibitor p35”
- Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy (2008, background): “However, it is known that apoptotic stimuli in immortalized Drosophila imaginal disc cells dramatically promote autonomous and non-autonomous proliferation causing aberrant overgrowths (Ryoo et al., 2004).”
- Programmed Cell Death in Animal Development and Disease (2011, neutral): “The Drosophila IAP family member Diap1 is essential for preventing inappropriate caspase activation and ubiquitous apoptosis (Goyal et al., 2000; Ryoo et al., 2004).”
- Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut (2009, background): “Lineage analysis suggests that, in well-fed flies, differentiated cells in the midgut epithelium turn over roughly weekly, as in mammals.”