Disentangling Genetic Variation for Resistance and Tolerance to Infectious Diseases in Animals
By Lars Råberg, D. Sim, Andrew F. Read. Science, 2007
771 citations recorded by the source corpus.
Subfields: Genetics, Parasitology, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/8048c4e34ebf17b27610d1787ef6f2b3c5f2a0bf
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In Genetics
In Public Health, Environmental and Occupational Health
Citations in the corpus
- Decomposing health: tolerance and resistance to parasites in animals (2009, background): “Still, it may often be possible to experimentally enhance the variation in infection intensity by using, for instance, several different parasite clones that vary in the infection intensity they induce (Råberg et al. 2007), chemotherapy to artificially reduce burdens in some animals, or to infect an”
- Self‐medication in insects: current evidence and future perspectives (2014, background): “Resistance is an individual’s ability to limit parasite burden (either by lowering infection risk and/or infection load), whereas tolerance is an individual’s ability to limit the damage caused at a given infection load (Råberg et al., 2007).”
- Future directions in breeding for disease resistance in aquaculture species (2017, background): “Disease resistance is often used as a generic term to describe the ability of the host to limit infection, or the consequences of infection, by reducing pathogen replication (Råberg et al., 2007; Doeschl-Wilson et al., 2012; Bishop and Woolliams, 2014), and the opposite can be considered as suscepti”
- Resilience in farm animals: biology, management, breeding and implications for animal welfare (2016, background): “For example, disease resistance and disease tolerance are generally negatively correlated, therefore individuals identified as susceptible to disease tend to be more tolerant, and conversely, individuals with resistant genotypes tend to be less tolerant (Raberg et al. 2007).”
- Estimating lion population variables: prey and disease effects in Kruger National Park, South Africa. (2010, background): “Often species respond to an emerging disease through rapid evolution that leads to resistance or tolerance (Råberg et al. 2007).”
- Virulence evolution and the trade‐off hypothesis: history, current state of affairs and the future (2009, background): “have linked virulence to other host traits like resistance or tolerance (Gandon & Michalakis, 2000; Gandon et al., 2002; Horak et al., 2006; Miller et al., 2007; Raberg et al., 2007).”
- Genomic responses in mouse models poorly mimic human inflammatory diseases (2013, neutral): “tolerance or resilience to infection (26, 27).”