Global metabolic profiling procedures for urine using UPLC–MS

By E. Want, Ian A. Wilson, H. Gika, Georgios Theodoridis, R. Plumb, J. Shockcor, Edward C. Holmes, Jeremy K. Nicholson. Nature Protocols, 2010

1,060 citations recorded by the source corpus.

Subfields: Complementary and alternative medicine, Molecular Biology, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/7f69e108a825c8790037c97d11f7fb290f5ce869

How researchers see this paper

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In Molecular Biology

1. David S. Wishart
2. Warwick B. Dunn
3. Royston Goodacre
4. Jianguo Xia
5. David Broadhurst
6. Anchi Guo
7. Craig Knox
8. R. Mandal

In Spectroscopy

1. David S. Wishart
2. Royston Goodacre
3. R. Mandal
4. David Broadhurst
5. Warwick B. Dunn
6. Ian A. Wilson
7. T. Millar
8. Jianguo Xia

Citations in the corpus

• The Human Urine Metabolome (2013, background): “In addition to these referential clinical chemistry studies, several groups have applied various ‘‘global’’ metabolomic or metabolite profiling methods to urine, such as high resolution nuclear magnetic resolution (NMR) spectroscopy [38,39,40], high performance liquid chromatography (HPLC) [41], hig”
• Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic studies (2018, background): “2011b) or < 30% (Lewis et al. 2016; Want et al. 2010) depending on the sample type, and it is recommended that the acceptance criterion for D-ratio is set to, at most, < 50% (preferably much lower).”
• TFOS DEWS II Tear Film Report (2017, background): “Metabolites are then identified through database searches, and their identities are confirmed by comparison of retention time and tandem mass spectra with pure standards [535].”