The single-end invasion: an asymmetric intermediate at the double-strand break to double-holliday junction transition of meiotic recombination.

By N. Hunter, N. Kleckner. Cell, 2001

690 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/7f570ac3662b16841fc660a83302fe7fe733a259

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. G. Börner
2. L. Symington
3. N. Hunter
4. N. Kleckner
5. Wolf-Dietrich Heyer
6. Xiaolan Zhao
7. L. Krejci
8. M. Špírek

In Molecular Biology

1. N. Hunter
2. G. Börner
3. L. Symington
4. N. Kleckner
5. Wolf-Dietrich Heyer
6. Jie Liu
7. Xiaolan Zhao
8. L. Krejci

Citations in the corpus

• Role of RAD52 Epistasis Group Genes in Homologous Recombination and Double-Strand Break Repair (2002, background): “Kinetic studies suggest that SEIs arise before dHJ inter- mediates and could be precursors to them or could be processed independently to form noncrossover products (11, 144).”
• Homologous recombination and its regulation (2012, background): “During meiosis, crossovers are formed by resolution of dHJs via the DSBR mechanism, while non-crossovers are primarily produced via SDSA mechanism (10,11).”
• Crossover/noncrossover differentiation, synaptonemal complex formation, and regulatory surveillance at the leptotene/zygotene transition of meiosis. (2004, methodology): “(*) “SEI3” and “SEI4” of Hunter and Kleckner (2001).”
• Meiotic Recombination: The Essence of Heredity. (2015, background): “…interdependence between the initiation of synapsis and the initial differentiation of crossover and noncrossover pathways, with SEIs being the earliest detectable crossover-specific joint molecules (see below) (Hunter and Kleckner 2001; Borner et al. 2004; Reynolds et al. 2013; Zhang et al. 2014a).”
• A meiotic time-course for Arabidopsis thaliana (2003, background): “At 5 h post transfer, SEI disappear, during pachytene, and are replaced by double Holliday junctions; crossovers finally appear at the end of pachytene, at 5.5 h post transfer (Padmore et al. 1991; Hunter and Kleckner 2001).”
• Regulation of homologous recombination in eukaryotes (2010, background): “These intermediates also appear to be metastable, because they can be visualized cytologically (Rad51 foci) (97) or identified physically (76, 77).”