Microbial modulation of innate defense: goblet cells and the intestinal mucus layer.

By B. Deplancke, H. Gaskins. American Journal of Clinical Nutrition, 2001

998 citations recorded by the source corpus.

Subfields: Food Science, Genetics, Surgery

View Paper: https://www.semanticscholar.org/paper/7e87290f94fa4f117cd7dc56531e936e4de883a0

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Citations in the corpus

Intestinal Barrier Dysfunction, LPS Translocation, and Disease Development (2020, background): “The amount and composition of the mucus layer reflects a balance between mucus secretion and its erosion and degradation by bacteria [14].”
The Hologenome Concept: Human, Animal and Plant Microbiota (2014, background): “It is well known that fasting leads to an increase in available mucins in the colon (Deplancke and Gaskins 2001), and those mucins are good nutrient sources for some gut bacteria (Larson et al. 1988).”
Application of prebiotics and probiotics in poultry production. (2003, background): “(Key words: intestinal microbiota, poultry, prebiotic, probiotic) 2003 Poultry Science 82:627–631”
Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa (2010, background): “This is a critical question since the Muc2-dependent mucus layer is one of the first anatomical features bacteria such as A/E pathogens must encounter before reaching the intestinal epithelium [33].”
Intestinal Goblet Cells and Mucins in Health and Disease: Recent Insights and Progress (2010, background): “Mucus layers also contain other goblet cell products, TFF3, RELMβ, and Fcgbp; antimicrobials peptides such as β defensin and lysozymes secreted by Paneth cells; and secretory IgA secreted by enterocytes [1, 2, 5, 10].”
Secretory IgA's Complex Roles in Immunity and Mucosal Homeostasis in the Gut (2011, background): “6 Immune exclusion: agglutination, entrapment, and clearance “Immune exclusion” generally refers to the ability of SIgA to prevent microbial pathogens and antigens such as toxins from gaining access to the intestinal epithelium through a stepwise series of events involving agglutination”
pH and Peptide Supply Can Radically Alter Bacterial Populations and Short-Chain Fatty Acid Ratios within Microbial Communities from the Human Colon (2005, background): “Shifts in microbial community structure caused by diet (32) also have the potential to influence interactions between gut microbes, gut epithelial cells, and the immune system (10, 28, 40).”
Effect of Probiotics on Broilers Performance (2006, background): “Mode of action of probiotics Immune enhancement: There is extensive information on the immune system (Schat and Myers, 1991; Kitagaw et al., 1998; Mayer, 1998; Muir, 1998; Hershberg and Mayer, 2000; Shanahan, 2000; Erickson and Hubbard, 2000; Jeurissen et al., 2000; Spellberg and Edwards, 2001; Toms”
Interaction between chicken intestinal microbiota and protein digestion (2016, background): “Indeed, bacteria have been reported to catalyse such functions (Deplancke and Gaskins, 2001; Hörmann et al., 2014).”