Bile acids as carcinogens in human gastrointestinal cancers.

By H. Bernstein, C. Bernstein, C. Payne, K. Dvor̆áková, H. Garewal. Mutation research, 2005

608 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/7dd1b1ef2b6952b12fe62e1ceac62dc1990add83

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. C. Hill
2. Julian R. Marchesi
3. Erwin G. Zoetendal

In Oncology

1. Michael A. Fischbach
2. Mohamed S. Donia

In Surgery

1. C. Hill

Citations in the corpus

• Bile salt biotransformations by human intestinal bacteria Published, JLR Papers in Press, November 18, 2005. (2006, background): “100 AM) (138); 2) it can cross biological membranes via passive diffusion; and 3) it can activate mammalian cell signaling pathways that are known to be involved in promoting carcinogenesis.”
• Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans. (2013, background): “Human studies have associated increased fecal secondary BAs with colon polyps (58) and colon cancer (59), and there is substantial experimental evidence that they have carcinogenic properties (7).”
• Bile Acids and the Gut Microbiome (2014, background): “bile of patients with colon cancer and some cholesterol gallstone disease is widely reported [15].”
• Fat, Fiber and Cancer Risk in African Americans and Rural Africans (2015, unknown): “Secondary bile acids have been shown to be carcinogenic in experimental models and multiple human studies have shown that their fecal levels are associated with cancer risk 10,24,25 .”
• Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome (2008, background): “However, because CRC is predominantly diagnosed in individuals 50 years of age (31), the effect of CRC on reproductive fitness in the ancestors of modern humans would have been negligible, and as such would not pose a significant counter selection to the shorter-term beneficial effects of BSH activi”