Network dynamics and cell physiology

By J. Tyson, Kathy Chen, Béla Novák. Nature reviews. Molecular cell biology, 2001

584 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/7d44346d08d47a3af94c2b71a38b34966599b677

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Citations in the corpus

Integrative analysis of cell cycle control in budding yeast. (2004, background): “The model is designed to have two coexisting, self-maintaining steady states: a G1 state, when Clbs are scarce and their antagonists (Cdh1 and CKIs) are abundant; and an S/G2/M state, when the reverse is true (Nasmyth, 1996; Novak and Tyson, 1997; Novak et al., 1998; Tyson and Novak, 2001; Tyson et ”
Introduction to systems biology. (2007, background): “Another aspect of systems biology is the construction of kinetic models of molecular network functioning as was introduced briefl y in the previous section [12, 17, 20].”
Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. (2003, background): “Excellent reviews from other perspectives can be found elsewhere [17,18 ,19–22,23 ,24 ,25], and also book-length treatments [26–29].”
Boolean Network Model Predicts Cell Cycle Sequence of Fission Yeast (2007, background): “The overall results obtained from our model are in accordance with the existing ODE model of fission yeast [10].”
Systems biology of stem cell fate and cellular reprogramming (2009, background): “This integrated experimental–theoretical approach has greatly enhanced our understanding of a wide range of complex mammalian biochemical system”
Organisms or biological individuals? Combining physiological and evolutionary individuality (2016, background): “Today, many biologists work on cell physiology (Tyson et al. 2001).”
Computational approaches to cellular rhythms (2002, background): “The interplay between oscillations and bistability has been addressed in detailed molecular models for the cell cycles of yeast and somatic cells, which are more complex owing to the existence of checkpoint”
Scale-free networks in cell biology (2005, background): “In the absence of comprehensive time-course datasets, dynamic reconstruction and analysis can usually be carried out only for small networks (Hoffmann et al., 2002; Lee et al., 2003; Tyson et al., 2001).”
A vision for the future of genomics research (2003, background): “A complete interaction map of the proteins in a cell, and their cellular locations, will serve as an atlas for the biological and medical explorations of cellular metabolis”
Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades (2004, background): “Multisite phosphorylation is a recurrent theme in a plethora of signaling systems, including the cell cycle (Tyson et al., 2001).”