A paracrine requirement for hedgehog signalling in cancer

By R. Yauch, S. Gould, S. Scales, T. Tang, H. Tian, C. Ahn, Derek Marshall, L. Fu, T. Januario, Dara Y. Kallop and 5 more. Nature, 2008

993 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/7c470773dded050086fe4c2bb6a229ffc7bd0f79

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. C. Abate-Shen
2. Jin Jiang
3. C. Hui
4. M. Shen

Citations in the corpus

• Hedgehog Signaling in Development and Cancer (2008, positive): “In Drosophila , Ci processing depends on the kinesin-like protein Costal-2 (Cos2) that acts as a molecular scaffold to bring Ci and its kinases together, leading to efficient phosphorylation of Ci (Zhang et al., 2005).”
• Molecular genetics of prostate cancer: new prospects for old challenges. (2010, background): “…role in prostate cancer progression, it remains unclear as to whether this occurs through an autocrine mechanism in epithelial cells (Karhadkar et al. 2004; Sanchez et al. 2004), or, alternatively, through paracrine signaling involving stromal components (Yauch et al. 2008; Shaw et al. 2009).”