Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms
By R. Mikkelsen, P. Wardman. Oncogene, 2003
610 citations recorded by the source corpus.
Subfields: Biophysics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/7c3f17a184c82d15f222acf515e032e4ef47a70a
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In Molecular Biology
Citations in the corpus
- Nitric oxide synthases: regulation and function. (2012, background): “This compound can cause oxidative damage, nitration, and S-nitrosylation of biomolecules including proteins, lipids, and DNA.”
- Metabolic oxidation/reduction reactions and cellular responses to ionizing radiation: A unifying concept in stress response biology (2004, methodology): “) are activated resulting in the transcription of downstream genes thought to be involved in the radiation response [20,69–72,85–90].”
- The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. (2004, background): “The involvement of ROS in primary pathological mechanisms is a feature to which radiation is perhaps the major contributor [107,126].”
- Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects. (2007, background): “1, adapted from a review discussing these species in the context of radiation damage [7], summarizes the main pathways to “reactive oxygen and nitrogen” species (actually also involving carbon, sulfur, and chlorine), illustrating the multiplicity of reactive radicals and nonradical molecules.”
- A review of soil NO transformation: associated processes and possible physiological significance on organisms (2015, background): “…et al., 2001, 2002 Damaging DNA, proteins and lipids NO-mediated oxidative reaction products (e.g. ONOO-) Various types of cells Lee et al., 2003; Mikkelsen and Wardman, 2003; Ridnour et al., 2004 Brain pathology Neurons Brown and Neher, 2010 Myocardial injury Cardiocytes Wang and Zweier,…”
- Cytokines in Radiobiological Responses: A Review (2012, neutral): “However, it is easy to see how, for example, cysteine oxidation may modulate the action of multiple redox-sensitive proteins (38) and one could imagine that there may be distinctive redox requirements for triggering of such molecules, which would be impacted by the basal redox status of the cell and”