Watching a Protein as it Functions with 150-ps Time-Resolved X-ray Crystallography
By F. Schotte, M. Lim, Timothy A. Jackson, A. Smirnov, J. Soman, J. Olson, G. Phillips, M. Wulff, P. Anfinrud. Science, 2003
707 citations recorded by the source corpus.
Subfields: Cell Biology, Molecular Biology, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/7c0db655469f33e14f423e11dba821e0c931a669
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- T. C. Terwilliger
- Pavel V. Afonine
- Paul D. Adams
- Alexandre Urzhumtsev
- M. Grimaldo
- F. Roosen‐Runge
- Buyong Ma
- Fajun Zhang
In Spectroscopy
- Paul D. Adams
- Pavel V. Afonine
- T. C. Terwilliger
- M. Grimaldo
- F. Roosen‐Runge
- Alexandre Urzhumtsev
- Fajun Zhang
- Frank Schreiber
Citations in the corpus
- Is allostery an intrinsic property of all dynamic proteins? (2004, background): “Recently, a novel application of time-resolved X-ray crysallography on myoglobin revealed that correlated side-chain motions play a role in protein function.(88)”
- Metrics for comparison of crystallographic maps (2014, methodology): “Note that using CCr( a, b), in contrast to D(q; a, b), applies not only to Fourier maps shown as series of masks but also to any continuous spectrum of colours or intensities (see, for example, Schotte et al., 2003).”
- Serial femtosecond crystallography: the first five years (2015, background): “This allows researchers to follow e.g. the very early events upon breaking of the haem iron–carbon monoxide bond in carbonmonoxy myoglobin (Schotte et al., 2003), or the isomerization of the cofactor in photoactive yellow protein (Jung et al., 2013; Schotte et al., 2012), as demonstrated recently…”
- Review of third and next generation synchrotron light sources (2005, methodology): “One very powerful tool in this context is time-resolved studies exploiting the pulsed structure of SR as it has been demonstrated in several cases (e.g. Schotte et al 2003).”
- A unified model of protein dynamics (2009, background): “Above 150 K, the CO also moves to other cavities, particularly to the Xe-1 pocket (state D), and returns from there to rebind (46).”
- Dynamics of proteins in solution (2019, background): “Time-resolved Laue X-ray crystallography achieved highresolution information on photo-activated protein dynamics in the crystalline state (Wulff et al., 1997; Srajer et al., 2001; Schotte et al., 2003, 2012; Aquila et al., 2012).”