Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2

By S. Coste, R. Kesterson, K. A. Heldwein, S. L. Stevens, Amanda Heard, Jacob H. Hollis, Susan E. Murray, Jennifer Hill, G. Pantely, A. Hohimer and 7 more. Nature Genetics, 2000

608 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Physiology, Social Psychology

View Paper: https://www.semanticscholar.org/paper/7a8b260148e7fcc5f817025d5439df3ba1936ccb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. Christine Marcelle Heim
2. C. Nemeroff
3. W. Craighead
4. M. Shugart
5. S. Maier
6. Elisabeth B. Binder
7. Michael Joseph Meaney
8. M. D. De Bellis

In Physiology

1. Linda R. Watkins
2. S. Maier
3. Clifford J. Woolf
4. R. Ji
5. G. Moalem-Taylor
6. P. Austin
7. Alban Latremoliere

In Social Psychology

1. Christine Marcelle Heim
2. W. Craighead
3. M. Shugart
4. C. Nemeroff
5. S. Maier
6. Linda R. Watkins
7. Elisabeth B. Binder
8. M. Weinstock

Citations in the corpus

• Neurobiological and psychiatric consequences of child abuse and neglect. (2010, background): “CRH-R2 deficient mice show exaggerated anxiety behaviors and are hypersensitive to stress (Bale et al., 2000; Coste et al., 2000).”
• Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse (2000, background): “…of CRF-related signaling molecules in the mouse model (Muglia et al., 1995; Smith et al., 1998; Karolyi et al., 1999; Bale et al., 2000; Coste et al., 2000; Kishimoto et al., 2000), and to attempt to define and, where possible, reconcile instances of ligand-receptor misalignment at…”
• The Corticosteroid Receptor Hypothesis of Depression (2000, result): “In contrast, CRH-R2 deficiency was shown to increase anxiety-like behavior in some (Bale et al. 2000; Kishimoto et al. 2000) but not all (Coste et al. 2000) studies, raising the possibility that the two so far identified CRH receptors mediate opposite effects on anxiety-like behavior.”
• Measuring normal and pathological anxiety-like behaviour in mice: a review. (2001, background): “[22] Coste SC, Kesterson RA, Heldwein KA, Stevens SL, Heard AD, Hollis JH, Murray SE, Hill JK, Pantely GA, Hohimer AR, Hatton DC, Phillips TJ, Finn DA, Low MJ, Rittenberg MB, Stenzel P, StenzelPoore MP.”
• Stressor controllability and learned helplessness: the roles of the dorsal raphe nucleus, serotonin, and corticotropin-releasing factor. (2005, background): “Indeed, deletion of the CRHR2(a) gene has been reported to either produce a phenotype characterized by increased anxietylike behavior (Bale et al., 2000; Kishimoto et al., 2000), or to have no effect on anxiety (Coste et al., 2000).”