Rostrolateral Prefrontal Cortex Involvement in Relational Integration during Reasoning

By Kalina Christoff, Vivek Prabhakaran, Jennifer Dorfman, Zuo Zhao, James K. Kroger, Keith J. Holyoak, John D. E. Gabrieli. NeuroImage, 2001

669 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/7a02b7a9deae8e9533aa2461a55fe17a867560a4

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In Cognitive Neuroscience

Citations in the corpus

Flexible Memories: Differential Roles for Medial Temporal Lobe and Prefrontal Cortex in Cross-Episode Binding (2010, background): “IFG has been implicated in non-mnemonic relational reasoning where multiple relationships must be considered to infer an unknown relationship (Christoff et al., 2001; Wendelken and Bunge, 2010), suggesting that PFC contributions to flexible AC transfer may be through inferential judgments from…”
The hippocampus and inferential reasoning: building memories to navigate future decisions (2012, background): “…supports memory for directly experienced associations, while structures in prefrontal cortex sub-serve relational reasoning processes (Robin and Holyoak, 1995; Christoff et al., 2001) whereby the contents of hippocampal representations are manipulated and recombined to support the inference itself.”
Process Overlap Theory: A Unified Account of the General Factor of Intelligence (2016, result): “…the ones found in Raven’s Progressive Matrices, probably the most typical test of Gf, consistently activate certain areas in the prefrontal cortex (Christoff et al., 2001; Prabhakaran, Smith, Desmond, Glover, & Gabrieli, 1997; Wharton et al., 2000), and this conclusion is further supported by…”
Emerging concepts for the dynamical organization of resting-state activity in the brain (2010, positive): “…suggested that this collection of regions subserves cognitive operations that are self-referential, a suggestion based on the observation that DMN regions overlap with regions that show activation in studies of self-referential behaviours 6,7 , such as autobiographic memory and self-judgments 8,9 .”
Brain correlates of aesthetic judgment of beauty (2006, neutral): “BA 10 is a very large brain region in humans: in volumetric terms probably the largest single architectonic region of the frontal lobes (Christoff et al., 2001).”
A Neuro-Cognitive Theory of Deductive Relational Reasoning with Mental Models and Visual Images (2009, background): “Christoff et al. (2001) tested the hypothesis that the process of relational integration is a component process of complex reasoning and that it recruits PFC.”
A symbolic-connectionist theory of relational inference and generalization. (2003, background): “(1999) found that the ability to represent and integrate multiple relations is profoundly impaired in patients with severe degeneration of prefrontal cortex, and neuroimaging studies have implicated dorsolateral prefrontal cortex in various tasks that require relational reasoning (Christoff et al., ”
Evaluative and generative modes of thought during the creative process (2012, background): “The RLPFC is activated during complex cognitive processing across a wide range of domains including complex reasoning (Christoff et al., 2001; Kroger et al., 2002; Monti et al., 2007), memory retrieval (Rugg and Wilding, 2000; Velanova et al., 2003), multi-tasking (Braver and Bongiolatti, 2002;…”
Neural Activity When People Solve Verbal Problems with Insight (2004, background): “Patients with prefrontal damage have particular difficulty integrating relations in reasoning tasks (Waltz et al. 1999), and when healthy subjects perform the same task, neural activity increases in rostrolateral prefrontal cortext (Christoff et al. 2001).”
Raven's Matrices and Working Memory: A Dual-Task Approach (2013, neutral): “…by Prabhakaran, Smith, Desmond, Glover, and Gabrieli (1997) in a study using functional magnetic resonance imaging (fMRI), while a later study by Christoff et al. (2001), also using fMRI and including response time, found increased involvement in the prefrontal cortex for those items that…”
Anterior prefrontal cortex: insights into function from anatomy and neuroimaging (2004, background): “and is essential for 'relational integration'; that is, the simultaneous consideration of multiple relation”
Function in the Human Connectome: Task-fMRI and Individual Differences in Behavior (2013, background): “The most commonly usedmeasure of fluid intelligence is Raven's Progressive Matrices (Christoff et al., 2001; Conway et al., 2005; Gray et al., 2003, 2005; Prabhakaran et al., 1997; Wendelken et al., 2008).”
Heterogeneity within the frontoparietal control network and its relationship to the default and dorsal attention networks (2017, background): “In contrast, FPCNA regions are activated when attention is directed toward one’s own thoughts and away from perceptual inputs (67–69), for example, during tasks that require metacognitive awareness (67, 70, 71), relational reasoning (72, 73), multitasking and complex task sets (64, 74–77), stimulusi”