Pharmaceutical Applications of Hot-Melt Extrusion: Part I
By Michael M. Crowley, Feng Zhang, M. Repka, Sridhar Thumma, Sampada B. Upadhye, Sunil Kumar Battu, J. Mcginity, C. Martin. Drug Development and Industrial Pharmacy, 2007
858 citations recorded by the source corpus.
Subfields: Molecular Biology, Pharmaceutical Science
View Paper: https://www.semanticscholar.org/paper/79ee57c6b7853411deb5e31cbba64285a897179b
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In Molecular Biology
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In Pharmaceutical Science
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Citations in the corpus
- Strategies to Address Low Drug Solubility in Discovery and Development (2013, background): “The mixture is subsequently forced through a die to produce an extrudate of uniform shape (Crowley et al., 2007).”
- Fused deposition modelling: Current status, methodology, applications and future prospects (2021, background): “It has been reported that HME, which is the process of pumping raw materials with a rotating screw under elevated temperature through a die into a product of uniform shape [260], allows for the fabrication of filaments with uniform quantity of API and good mechanical properties [261–263].”
- Effect of geometry on drug release from 3D printed tablets. (2015, methodology): “Several research groups have demonstrated HME processes as a viable method to prepare a wide range of accepted pharmaceutical drug delivery systems, including granules, pellets, transdermal patches, transmucosal films systems and implants (Breitenbach, 2002; Crowley et al., 2007; Fonteyne et al., 20”