Heterochromatin and Epigenetic Control of Gene Expression

By S. Grewal, D. Moazed. Science, 2003

1,059 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/79caa1c2ff4d4cfb8d756e34e64d131f48f39524

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In Molecular Biology

Citations in the corpus

Nickel: Human Health and Environmental Toxicology (2020, background): “DNA methylation is involved in the regulation of many cellular processes, including chromatin structure and remodeling, genomic imprinting, chromosome stability and gene transcription [89].”
From silencing to gene expression: real-time analysis in single cells. (2004, methodology): “Per- pSV2-YFP-lac repressor-C1 and pSV2-YFP-C1 were previously described (Tsukamoto et al., 2000). pSV2-CFP-lac repressor-C1 washaps the high degree of complexity revealed in the studconstructed by replacing the coding region of YFP with CFP.ies of heterochromatin structure and regulation (repTet-On”
HP1 and the dynamics of heterochromatin maintenance (2004, background): “This propagation would involve a 'self-sustaining' loop, in which methylated H3-K9 histones bind to HP1; which in turn recruits more H3-K9 histone methyltransferas”
The mammalian epigenome. (2007, background): “In yeast (which lack DNA methylation), interactions between hypoacetylated histones and SIR proteins ( S. cerevisiae ) or between H3K9 methylated histones and the Swi6 chromodomain ( S. pombe ) maintain the heterochromatic state through cell division (Grewal and Moazed, 2003).”
The many faces of the helix-turn-helix domain: transcription regulation and beyond. (2005, background): “Furthermore, the regulators of chromatin dynamics, such as the histone deacetylases and associated Swi2 ATPases took up the role of transcriptional repressors [181], and probably resulted in the ancestral prokaryote-type repressors becoming superfluous.”