Cardiovascular actions of insulin.
By R. Muniyappa, M. Montagnani, K. Koh, M. Quon. Endocrine reviews, 2007
832 citations recorded by the source corpus.
Subfields: Epidemiology, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/79316af22a4872dc63bb152a06327744d6d4d3f5
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Citations in the corpus
- Adiponectin Regulation and Function (2018, neutral): “Insulin signals the release of NO through classic insulin signaling pathways, primarily PI3K-Akt activation (210).”
- Cardiac remodeling in obesity. (2008, background): “The topic of vascular dysfunction in obesity is large, and we will not attempt to review it in any detail in this paper but will refer the reader to a comprehensive recent review in this area (247).”
- Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. (2008, background): “In addition to these classical insulin target tissues, there are many other important physiological targets of insulin including the brain, pancreatic beta cells, heart, and vascular endothelium that help to coordinate and couple metabolic and cardiovascular homeostasis under healthy conditions (4, ”
- A prospective randomised multi-centre controlled trial on tight glucose control by intensive insulin therapy in adult intensive care units: the Glucontrol study (2009, neutral): “insulin [28].”
- Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities (2010, neutral): “In endothelial cells, insulin activates endothelial nitric oxide synthase, resulting in vasodilation (227, 251).”
- Atherosclerotic Cardiovascular Disease and Heart Failure in Type 2 Diabetes – Mechanisms, Management, and Clinical Considerations (2016, neutral): “Insulin stimulates endothelial NO synthase–induced production of NO by endothelial cells via the PI3-kinase/Akt pathway, and defects along the insulin signaling pathway seen in insulin resistance and diabetes mellitus result in decreased endothelial NO synthase activity and decreased NO production, ”