Eukaryotic cytosine methyltransferases.

By M. Goll, T. Bestor. Annual Review of Biochemistry, 2005

2,116 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/7873c89c32a53f5e3463cc5042ff06e192fe8d7b

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In Molecular Biology

Citations in the corpus

The Honey Bee Epigenomes: Differential Methylation of Brain DNA in Queens and Workers (2010, background): “Given the proposed role of cytosine methylation in defense against genomic parasites in plants and vertebrates [7], the lack of methylation in ALU repeats and mariner transposons suggests that these mobile elements do not significantly impact on genome stability in honey bees.”
Base-Resolution Analysis of 5-Hydroxymethylcytosine in the Mammalian Genome (2012, neutral): “…is symmetric, and the maintenance methyltransferase DNMT1 ensures efficient propagation of symmetric 5mCG during cell division, thus providing one of the central modes of epigenetic inheritance (Bird, 2011; Chen and Riggs, 2011; Goll and Bestor, 2005; Jaenisch and Bird, 2003; Wigler et al., 1981).”
The mammalian epigenome. (2007, background): “the presence of methylation in the CpG dinucleotide in the complementary template strand (Bird, 2002; Goll and Bestor, 2005).”
H1 linker histone promotes epigenetic silencing by regulating both DNA methylation and histone H3 methylation (2013, background): “There are two classes of mammalian DNA methyltransferases (DNMTs), one that functions primarily to establish DNA methylation de novo (DNMT3A and DNMT3B) and the other to maintain it (DNMT1) (3).”
Chromatin Structure and the Inheritance of Epigenetic Information (2010, background): “Cytosine methylation is required for development in eukaryotes with large genome”
The mysterious presence of a 5-methylcytosine oxidase in the Drosophila genome (2013, background): “From these data, it appears that Dnmt2 and dTet expression levels are close to zero at embryonic stages 0–2 h, the time point from which Drosophila embryos were collected by Raddatz et al. for bisulfite sequencing analysis.23 Combination of these data clearly suggests that searches for modified cyto”
Conservation and divergence of methylation patterning in plants and animals (2010, background): “Furthermore, the lack of CHG andCHHmethylation targeted to transposons is consistent with the apparent absence of a Dnmt3/DRM2 homolog in Chlamydomonas (8, 9), and that the closest CMT3 homolog is highly diverged relative to flowering plants (Fig.”
DNA Demethylation Dynamics (2011, background): “…gene silencing that leads to genomic imprinting, X chromosome inactivation, suppression of transposable elements, and the establishment and maintenance of stable cellular identities (Bird, 2002; De Carvalho et al., 2010; Deaton and Bird, 2011; Goll and Bestor, 2005; Jaenisch and Bird, 2003).”