'Racial' differences in genetic effects for complex diseases
By John P. A. Ioannidis, E. Ntzani, Thomas A. Trikalinos. 2004
456 citations recorded by the source corpus.
Subfields: Genetics
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In Genetics
- Paul F. O'Reilly
- David Altshuler
- Robert M. Plenge
- Jack Euesden
- Shaun Purcell
- Cathryn M. Lewis
- Matthew Stephens
- Shing-Wan Choi
Citations in the corpus
- Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study (2013, unknown): “consistent with prior meta-analyses of generalization [18].”
- An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis. (2017, background): “However, previous work shows that many schizophrenia risk alleles are shared across ethnic groups, predating African-European divergence (41,42).”
- Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database (2008, unknown): “BDNF Zintzaras, 2007 270C/T 1,866 (5) 4,091 (8) T vs.”
- Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. (2005, methodology): “2003), because we hypothesized that a true susceptibility allele would have an effect in both populations, despite possible genetic, ethnic, or clinical differences (Ioannidis et al. 2004).”
- STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement (2009, unknown): “Meta-analyses of 43 gene-disease associations comprising 697 individual studies showed consistent associations across groups of different ethnic origin [80], and thus provide evidence against a large effect of population stratification, hidden or otherwise.”