Telomere-end processing: The terminal nucleotidesof human chromosomes

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Human telomere, oncogenic promoter and 5′-UTR G-quadruplexes: diverse higher order DNA and RNA targets for cancer therapeutics (2007, background): “Telomeric DNA ends are composed of both duplex and guanine-rich 30-overhang segments, with the former progressively decreasing in length after each round of cell division in somatic cells (82).”
How shelterin protects mammalian telomeres. (2008, background): “In contrast, the last base of the 3′ overhang is variable and appears to be almost random in telomerase-negative cells (167).”
Shelterin: the protein complex that shapes and safeguards human telomeres. (2005, unknown): “In a tour de force, Sfeir et al. (2005) were able to determine the sequence at the 3 and 5 ends of human chromosomes.”
Quadruplex DNA: sequence, topology and structure (2006, background): “Formation of these quadruplex structures at telomere ends is possible since the terminal nucleotides at the 30 ends of all telomeric DNAs are single-stranded (9,10), albeit in association with single-strand-binding proteins, such as hPOT1 in Homo sapiens (11,12), where the single-strand overhang is ”