For the long run: maintaining germinal niches in the adult brain.

By Arturo Alvarez-Buylla, Daniel A. Lim. 2004

1,390 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “…and properties of neural precursor subtypes in the adult CNS, the supporting local environment , and sequential steps of adult neurogenesis, ranging from neural precursor proliferation to synaptic integration of newborn neurons (Alvarez-Buylla and Lim, 2004; Duan et al., 2008; Lledo et al., 2006).”
The endocannabinoid system drives neural progenitor proliferation (2005, positive): “Growth factors, such as epidermal and fibroblast-derived growth factor (EGF, FGF-2), act as key regulators of NP cell proliferation and differentiation (13, 14).”
Synaptic integration and plasticity of new neurons in the adult hippocampus (2008, methodology): “Aided by new methodologies for birth-dating and tracking new neurons in the adult brain, recent studies have elucidated the basic process of adult neurogenesis (Alvarez-Buylla & Lim, 2004; Ming & Song, 2005; Lledo et al. 2006; Zhao et al. 2008).”
Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis (2010, background): “Several signaling molecules, including Wnt, Noggin/BMP, Shh, and Notch, regulate adult NSC self-maintenance, proliferation, and progenitor differentiation [13,14].”
DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212 (2009, positive): “Adult neurogenesis occurs in a special microenvironment, named ‘‘niche’’ (Alvarez-Buylla and Lim, 2004; Lledo et al., 2006; Ming and Song, 2005; Ninkovic and Gotz, 2007; Zhao et al., 2008).”
Mechanisms and functional implications of adult neurogenesis. (2008, positive): “Proliferating cells and putative neural progenitors in both SGZ and SVZ are closely associated with the vasculature, indicating that factors released from the blood vessels may have a direct impact on adult neural progenitors (Alvarez-Buylla and Lim, 2004; Palmer et al., 2000).”
Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche. (2006, background): “These type B cells function as the primary progenitors of new neurons in the adult mouse forebrain and generate transient amplifying type C cells, which in turn differentiate into neuroblasts that migrate to the olfactory bulb (OB) (reviewed in Alvarez-Buylla and Lim, 2004).”